Edwin Brant Frost II (July 16, 1866 – May 14, 1935) was an American astronomer.
He was born in Brattleboro, Vermont. His father, Carlton Pennington Frost, was dean of Dartmouth Medical School.
Frost graduated from Dartmouth in 1886. He continued his education as a post-graduate student in chemistry and in 1887 became an instructor in physics while only 21 years old. In 1890 Frost went abroad to Europe and ended up researching stellar spectroscopy under Hermann Vogel in Potsdam. He returned to Dartmouth in 1892 as an assistant professor of astronomy.